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Tophat/RNA-seq Analysis Nostalgia

Recently just started playing with TopHat, after a while back, for doing gene expression quantitation using  RNA-seq data and got all nostalgic about RNA-seq analysis over the years. Although there are...

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Bayesian Approach to Single-Cell RNA-Seq Differential Expression Analysis

Just a few weeks ago Nature Methods published an interesting paper on Bayesian approach that takes care of technical variations in Single Cell RNA-seq data and perform differential expression analysis...

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kallisto paper summary: Near-optimal RNA-seq quantification

In case you missed it, kallisto, the new RNA-seq quantification method from Lior Pachter‘s group, was one of the biggest highlights from this year’s The Biology of the Genomes conference. kallisto team...

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